Cerebral Protein Synthesis
نویسندگان
چکیده
منابع مشابه
Cerebral protein synthesis in a genetic mouse model of phenylketonuria.
Local rates of cerebral protein synthesis (lCPS(leu)) were measured with the quantitative autoradiographic [1-(14)C]leucine method in a genetic mouse model (Pah(enu2)) of phenylketonuria. As in the human disease, Pah(enu2) mice have a mutation in the gene for phenylalanine hydroxylase. We compared adult homozygous (HMZ) and heterozygous (HTZ) Pah(enu2) mice with the background strain (BTBR). Ar...
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When brain protein synthesis is inhibited shortly before or after training, retention is normal for a few hours but subsequently is severely impaired 1,7,1°. When inhibition is initiated 30 min or longer after training, memory is not affected. These findings have been obtained with rodents, chicks and fish, using a variety of learning tasks including discrimination problems, passive avoidance, ...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1971
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(19)77194-4